Investigation of cationic ring-opening polymerization of 2-oxazolines in the “green” solvent dihydrolevoglucosenone

• Solomiia Borova and
• Robert Luxenhofer

Beilstein J. Org. Chem. 2023, 19, 217–230, doi:10.3762/bjoc.19.21

• hydrophilic polymers with a good safety and environmental profile has been a hot topic in recent years. Specifically, the search for more benign solvents for the polymerization of 2-alkyl-2-oxazolines has been ongoing for some time. Poly(2-oxazoline)s (POx) are a family of polymers investigated for a range of

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

• Luke O. Jones,
• Leah Williams,
• Tasmin Boam,
• Martin Kalmet,
• Chidubem Oguike and
• Fiona L. Hatton

Beilstein J. Org. Chem. 2021, 17, 2553–2569, doi:10.3762/bjoc.17.171

• polymer selection. For example, altering the ratio of hydrophobic and hydrophilic polymers in the final cryogel structure can allow for fine tuning of the responsive behaviour [33][34]. At specific and unique temperatures, phase changes occur to a temperature-responsive polymer, physically changing the

Photoinduced post-modification of graphitic carbon nitride-embedded hydrogels: synthesis of 'hydrophobic hydrogels' and pore substructuring

• Cansu Esen and
• Baris Kumru

Beilstein J. Org. Chem. 2021, 17, 1323–1334, doi:10.3762/bjoc.17.92

• Cansu Esen Baris Kumru Max Planck Institute of Colloids and Interfaces, Department of Colloid Chemistry, Am Mühlenberg 1, 14476 Potsdam, Germany 10.3762/bjoc.17.92 Abstract Hydrogels are a special class of crosslinked hydrophilic polymers with a high water content through their porous structures

Versatile synthesis of end-reactive polyrotaxanes applicable to fabrication of supramolecular biomaterials

• Atsushi Tamura,
• Asato Tonegawa,
• Yoshinori Arisaka and
• Nobuhiko Yui

Beilstein J. Org. Chem. 2016, 12, 2883–2892, doi:10.3762/bjoc.12.287

• click reactions, including ligand molecules for active targeting, radioactive molecules for in vivo imaging, hydrophobic polymers for the surface immobilization of PRXs, and hydrophilic polymers for acquiring water solubility. Accordingly, the azide group-terminated end-reactive 4a and 4b are expected

Towards potential nanoparticle contrast agents: Synthesis of new functionalized PEG bisphosphonates

• Souad Kachbi-Khelfallah,
• Maelle Monteil,
• Margery Cortes-Clerget,
• Evelyne Migianu-Griffoni,
• Jean-Luc Pirat,
• Olivier Gager,
• Julia Deschamp and
• Marc Lecouvey

Beilstein J. Org. Chem. 2016, 12, 1366–1371, doi:10.3762/bjoc.12.130

• obtained must be stable in the various biological compartments and they must be stealthy to avoid the elimination by macrophages. For this purpose, appropriate coatings have already been reported [3][4]. Some of which consist in the NP surface modification using hydrophilic polymers (dextran, PEG) or

Formation of nanoparticles by cooperative inclusion between (S)-camptothecin-modified dextrans and β-cyclodextrin polymers

• Thorbjørn Terndrup Nielsen,
• Catherine Amiel,
• Laurent Duroux,
• Kim Lambertsen Larsen,
• Lars Wagner Städe,
• Reinhard Wimmer and
• Véronique Wintgens

Beilstein J. Org. Chem. 2015, 11, 147–154, doi:10.3762/bjoc.11.14

• the inactive and toxic carboxylate form. A way to circumvent these drawbacks can be to conjugate the CPT to hydrophilic polymers and hereby creating a water-soluble polymeric CPT prodrug whereby the apparent aqueous solubility of the drug is increased. Furthermore, modification of the CPT hydroxy

Preparation and evaluation of cyclodextrin polypseudorotaxane with PEGylated liposome as a sustained release drug carrier

• Kayoko Hayashida,
• Taishi Higashi,
• Daichi Kono,
• Keiichi Motoyama,
• Koki Wada and
• Hidetoshi Arima

Beilstein J. Org. Chem. 2014, 10, 2756–2764, doi:10.3762/bjoc.10.292

• rapid removal from the systemic circulation by the reticuloendothelial system (RES). To produce long-circulating LPs, hydrophilic polymers, carbohydrates, peptides and proteins have been used to modify the surface of LPs [29]. Additionally, the targeting efficiency of LPs has been improved by appending

Chiral recognition of ephedrine: Hydrophilic polymers bearing β-cyclodextrin moieties as chiral sensitive host molecules

• Sabrina Gingter and
• Helmut Ritter

Beilstein J. Org. Chem. 2011, 7, 1516–1519, doi:10.3762/bjoc.7.177

Ring opening metathesis polymerization-derived block copolymers bearing chelating ligands: synthesis, metal immobilization and use in hydroformylation under micellar conditions

• Gajanan M. Pawar,
• Jochen Weckesser,
• Siegfried Blechert and
• Michael R. Buchmeiser

Beilstein J. Org. Chem. 2010, 6, No. 28, doi:10.3762/bjoc.6.28

• micellar catalytic set up are discussed. Keywords: block copolymers; catalysis; hydrophilic polymers; metathesis; micelles; Introduction Catalysts bound to amphiphilic block copolymers find increasing use in micellar catalysis since they combine the advantages of both homogeneous and heterogeneous